| 王 彬，张其中，陈本亮，付耀武.40 种中草药杀灭离体多子小瓜虫效果研究[J].广东农业科学,2017,44(7):147-153 |
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40 种中草药杀灭离体多子小瓜虫效果研究 |
| Antiparasitic efficacy of 40 Chinese herbal medicines against Ichthyophthirius multifiliis in vitro |
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| DOI：10.16768/j.issn.1004-874X.2017.07.023 |
| 中文关键词: 中草药 生姜 杀虫活性 多子小瓜虫 |
| 英文关键词: Chinese herbal medicine Zingiber officinale antiparasitic activity Ichthyophthirius multifiliis |
| 基金项目:广东省海洋渔业科技攻关与研发项目（A201501B09）；广州市科技计划项目（201604020040） |
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| 中文摘要: |
| 研究了40 种中草药不同浓度水提物对多子小瓜虫（Ichthyophthirius multifiliis）的离体杀灭效
果，结果表明：夏枯草、仙鹤草和三七等18 种中草药在浓度为50 g/L 时才能在4 h 内杀灭多子小瓜虫滋养
体；药物浓度为10 g/L 时，槐花、皂角刺和毛冬青等13 种中草药可杀灭滋养体；药物浓度为1 g/L 时，紫荆
和鹅不食草即可杀灭滋养体；药物浓度为0.1 g/L 时，只有生姜能杀灭多子小瓜虫滋养体。生姜水提物对滋养
体和幼虫的最低致死浓度分别为100、50 mg/L，半数有效浓度分别为30.3、15.7 mg/L，100 mg/L 可完全抑制
包囊孵化。由此可见生姜是一种可有效杀灭多子小瓜虫的中草药。 |
| 英文摘要: |
| The present study investigated the in vitro antiparasitical efficacy of 40 Chinese herbal medicines
water extracts against Ichthyophthirius multifiliis. The results showed that the water extracts of Prunella vulgaris，
Agrimonia eupatoria，Panax notoginseng，etc，at the concentration of 50 g/L could kill all trophonts within 4 h，
the water extracts of Sophora japonica，Gleditsia sinensis，Llex pubescens and so forth at the concentration of 10 g/L
could kill all trophonts，the water extracts of Cercis chinensis and Herba hydrocotylis resulted in 100% mortality
of trophonts at the concentration of 1 g/L，the water extract of Zingiber officinale at the concentration of 0.1 g/L
resulted in 100% mortality of trophonts. The water extract of Z. officinal showed the highest antiprotozoal efficacy
against trophonts and theronts，and the lethal concentrations to trophonts and theronts were 100 and 50 mg/L，
respectively. The 4-h median effective concentration（ EC50） values of water extract of Z. officinal to trophonts and
theronts were 30.3 mg/L and 15.7 mg/L，respectively. The water extract of Z. officinal at a concentration of 100 mg/L
eliminated the reproduction of all encysted tomonts. The results indicate that Z. officinal is a potential new drug for the
control of ichthyophthiriasis. |
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