| 庞纪彩，高风英，卢迈新，朱华平，可小丽，黄樟翰.鱼类MHC II 类基因及其研究进展[J].广东农业科学,2012,39(3):141-145 |
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鱼类MHC II 类基因及其研究进展 |
| Progress of major histocompatibility complex （MHC）II gene and relevant gene research in fish |
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| DOI： |
| 中文关键词: 鱼类 MHC II 基因 免疫 抗病育种 |
| 英文关键词: fish major histocompatibility complex (MHC) II gene immune disease resistance |
| 基金项目: |
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| 摘要点击次数: 1566 |
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| 中文摘要: |
| 主要组织相容性复合体（Major Histocompatibility Complex，MHC）是广泛存在于脊椎动物体内，与免疫相关并编码免疫蛋白受体的基因群。在鱼类中，由于其高度的多态性，使其在遗传、进化以及抗病育种等方面备受青睐。从MHC II 类基因的分子结构与功能、克隆及组织分布、遗传特征及基因多态性与抗病力的关系以及MHC II 类基因在鱼类研究中的应用进行综述，并对鱼类MHC 域类基因未来的研究重点进行展望。 |
| 英文摘要: |
| Major histocompatibility complex (MHC) is widespread in vertebrates, and is a gene cluster which encoding immune and immune-related protein receptor. In fish, because of its high polymorphism, it is so favored to the genetic, evolutionary and breeding for disease resistance and so on. The molecular structure and function, cloning and tissue distribution of the MHC II genes, and the
relationship between genetic characteristics and disease resistance gene polymorphism were summarized in this paper; and research priorities in fish MHC II in the future were discussed. |
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