| 刘磊1 2 周绪正2 李冰2 李金善2 魏小娟2 牛建荣2 邢守叶1 2 张继瑜2.伊维菌素纳米乳对牛的安全性研究[J].广东农业科学,2014,41(2):125-127 |
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伊维菌素纳米乳对牛的安全性研究 |
| Safety test of Ivermectin nanoemulsion on beef cattle |
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| DOI： |
| 中文关键词: 伊维菌素 纳米乳 肉牛 安全性试验 |
| 英文关键词: Ivermectin nanoemulsion beef cattle safety test |
| 基金项目:国家现代农业肉牛牦牛产业技术体系建设专项
资金CARS-38重点牧区生产生态生活保障技术集成与示范
2012BAD13BOO |
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| 摘要点击次数: 1464 |
| 全文下载次数: 734 |
| 中文摘要: |
| 研究了新型伊维菌素纳米乳对靶动物牛的安全性。将24 头牛随机分成4 组设空白对照、1 倍推荐剂
量3 倍剂量5 倍剂量处理各处理6 头牛分别按照0，0.2，0.6，1.0 mg/kg 体重给药，二次给药后于颈静脉采集全血和抗凝血进行血液生化和血液学检测。结果显示，所有试验牛在给药后的各项血液学及血液生化指标均在正常值范
围内各项指标变化差异不显著。各处理试验牛的心、肝、肺、肾等实质器官病理检测结果无明显异常。试验结果表
明，该新型伊维菌素纳米乳制剂对牛是安全的。 |
| 英文摘要: |
| To evaluate the safety of Ivermectin nanoemulsion on beef cattle, twenty four beef cattles were divided into
4 groups at random, including the control group 0 mg/kg, one time of the recommended dose group (0.2 mg/kg), three
times of the recommended dose group (0.6 mg/kg), five times of the recommended dose group (1.0 mg/kg), and the blood
samples were collected after the second administration (8 d)for blood biochemical and blood analysis. The results showed
that the indicators of all cattle were within the normal range, the indicators had no significant differences. The pathological
changes of heart, liver, lung and kidney had no obvious abnormalities. It suggested that the Ivermectin nanoemulsion was
safe for the target animal. |
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