| 林春华，乔燕春，谭雪，郭爽.野生蔬菜白簕的安全性评价[J].广东农业科学,2014,41(8):47-51 |
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野生蔬菜白簕的安全性评价 |
| Safety evaluation of Acanthopanax trifoliatus, a wild vegetable |
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| DOI： |
| 中文关键词: 白簕 毒理学 安全性 野生蔬菜 |
| 英文关键词: Acanthopanax trifoliatus toxicology safety wild vegetable |
| 基金项目:广东省科技攻关项目（2008B021500011）；广东
省教育部产学研结合项目（2010B090400492） |
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| 中文摘要: |
| 采用急性经口毒性、30 d喂养、遗传毒性等试验研究白簕的食用安全性。急性经口毒性试验显示，白簕
半致死量LD50跃40 g/kg；30 d喂养试验白簕对SD 大鼠的生长影响不明显，对血液生化指标影响也不明显；病理检测
表明，13.34、6.67、3.34 g/kg窑d 等3 种剂量不会导致大鼠脾、肝、肾脏等器官的损害；在试验最大剂量范围内，骨髓微核
试验和小鼠睾丸染色体畸变试验结果均为阴性。 |
| 英文摘要: |
| The techniques including acute oral toxicity, long-term feeding (30 days) and genetic toxicity test were
employed to evaluate the safety performance of a wild vegetable A canthopanax trifoliatus. The results showed that the
median lethal dose (LD50) was more than 40 g/kg. Long-term feeding of the SD rats with A. trifoliatus for 30 days showed
no significant effect on the growth and blood biochemical indicators of the rats. Moreover, the pathology test result showed
that three dosages (13.34, 6.67, 3.34g/kg of A. trifoliatus in the feeding experiment couldnt induce any damage on the
spleen, liver and kidney of the rats. Even after the maximum dose(13.4 g/kg) treatment, the test results of Micronucleus test
of bone marrow cell and chromosome aberration in mice were all negative. |
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