| 李 潇，靳文博，李若静，祝欢欢，赵晓晓，曹谨玲.氟在中华圆田螺体内富集及其对肝胰脏
免疫相关酶的影响[J].广东农业科学,2015,42(21):124-128 |
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氟在中华圆田螺体内富集及其对肝胰脏
免疫相关酶的影响 |
| Tissue distribution of fluoride and its effects on immunerelatedenzymes activities of hepatopancreasin Cipangopaludina cahayensis |
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| DOI： |
| 中文关键词: 氟 中华圆田螺 生物富集 免疫相关酶 |
| 英文关键词: fluoride Cipangopaludina cahayensis biological accumulation immune-related enzyme |
| 基金项目: |
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| 中文摘要: |
| 以中华圆田螺为试验材料，研究水环境中不同浓度（0、40、80、160 mg/L）氟暴露条件下，氟在
其体内的富集及对肝胰脏免疫相关酶，如酸性磷酸酶（ACP）、碱性磷酸酶（AKP）和过氧化氢酶（CAT）活
性的影响。结果显示，在不同浓度氟化钠连续暴露30、60 d 后，与对照组比较，不同浓度氟暴露组中华圆田螺
不同组织中的氟含量均显著高于对照组，且随着氟暴露剂量的升高，呈现先升后降趋势，表明氟在中华圆田螺
不同组织中的浓度已经达到平衡；在整个染毒过程中，染毒组ACP 和AKP 活性与对照组相比呈先降后升的趋
势。氟暴露30 d，高浓度组ACP 和AKP 活性极显著高于对照组，氟暴露60 d，所有染毒组ACP 和AKP 活性均
显著低于对照组；染毒组CAT 活性与对照组相比呈先升后降再升趋势，且80 mg/L 组和160 mg/L 组CAT 活性
极显著低于对照组。 |
| 英文摘要: |
| Tissue distribution of fluoride and its effects on the activities of immune-related enzymes（ACP，
AKP and CAT）were examined in hepatopancreas of Cipangopaludina cahayensis exposed to different concentrations
of fluoride for 60 days. The results showed that the fluoride accumulation in different tissues after exposed to fluoride
significantly increased compared with the control group and the trend which increased and then decreased with the level
and duration of exposure was found. Stead state was achieved under the experimental conditions. The activities of ACP
and AKP first decreased and then increased during the fluoride exposure. After 30 days of exposure，the activities of
ACP and AKP in hepatopancreas exposed to the highest concentration of fluoride highly significantly elevated compared
with the control group. After exposure for 60 days，the activities of ACP and AKP in all fluoride-exposed C. cahayensis
were remarkably lower than those in the control mudsnail. The CAT activity increased first and then decreased and highly
significantly decreased in mudsnail exposed to 80 mg/L
and 160 mg/L of fluoride relative to the control during the
whole exposure. |
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