郑 霞,朱四元,吴端钦,戴求仲,唐守伟.植物SUMO 化修饰研究进展[J].广东农业科学,2015,42(22):113-119 |
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植物SUMO 化修饰研究进展 |
Advances of sumoylation in plants |
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DOI: |
中文关键词: 小泛素修饰蛋白 SUMO 化 生长发育 拟南芥 |
英文关键词: SUMO sumoylation growth and development Arabidopsis thaliana |
基金项目:中国农业科学院农业科学与技术创新工程
专项(ASTIP-IBFC02) |
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中文摘要: |
SUMO(Small ubiquitin-related modifier)化作为一种重要的真核生物翻译后修饰方式,广泛参与
真核细胞的各种代谢调控过程。SUMO 化修饰过程是一个动态、可逆的循环,需要经过一系列步骤,如SUMO
分子的活化、E1 激活酶、E2 缀合酶、E3 连接酶和特异性蛋白酶的去SUMO 化。植物的SUMO 化修饰参与了植
物对激素的响应、花的发育、开花控制、营养元素的吸收和逆境响应等重要生物学过程。近年来,SUMO 化已
成为植物功能基因研究中的新生长点。以拟南芥和水稻为主,综述了SUMO 化修饰过程的组成成分、SUMO
化与植物对激素响应的关系、SUMO 化参与的植物开花控制、SUMO 化与植物对非生物胁迫的响应等方面的研
究现状,并对植物SUMO 化研究中存在的问题提出建议,以期更好地理解SUMO 化修饰在植物生长发育中的
作用。 |
英文摘要: |
Sumoylation is one of the essential post-translational modifications in eukaryotes,and it plays an
important role in various cellular regulatory processes. Sumoylation is a dynamic,reversible cycle,consisted of a series
of biochemical reactions,including SUMO E1 activation,E2 conjugation,E3 ligation and deconjugation of SUMO
substrates catalyzed by ubiquitin-like SUMO-specific proteases. Sumoylation plays key roles in hormone response,
flower development,flowering time regulation,nutrient absorption and environmental adversities. In recent years,
sumoylation has become the new growth point of functional gene research in plants. Following is a brief overview of
the current understanding of sumoylation in Arabidopsis and rice,we first introduce the important components in
the sumoylation pathway,and then review the current progress that SUMO modification regulates plant growth and
development,including the response to signal of hormone and abiotic stress,flower development and flowering time
regulation. Finally,suggestions are presented for future research of sumoylation according to previous studies. It is
expected to provide a basis for better understanding the roles of sumoylation of proteins in plants. |
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