| 潘荣杨，张 哲，高 宁，陈赞谋，李加琪，张 豪.基因组选择一步法理论及应用研究进展[J].广东农业科学,2016,43(9):124-131 |
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基因组选择一步法理论及应用研究进展 |
| Research progress in Single step procedure theory and application in genomic selection |
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| DOI：10.16968/j.issn.1004-894X.2016.09.019 |
| 中文关键词: 基因组选择 遗传评定 一步法 |
| 英文关键词: genomic selection genetic evaluation single step procedure |
| 基金项目:国家自然科学基金（31200925）；国家现代农业产业技术体系专项（CARS-36） |
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| 中文摘要: |
| 基因组选择（Genomic selection，GS）是一种新兴的畜禽遗传评定方法，较传统方法有明显优
势，近十几年来成为畜禽遗传评定研究热点。但基因分型成本较高，实际育种过程中不可能对所有个体进
行基因型检测，致使某些经济价值较小物种实施GS 受限。一步法（Single step procedure）有效解决了这个
问题。一步法既能将全基因组遗传标记用于畜禽遗传评定，又能将未经基因分型的个体全部纳入遗传评定
模型，在猪、鸡等群体的基因组选择中应用备受关注。介绍了基因组选择一步法的原理，综述了其应用效果
及相关问题等。 |
| 英文摘要: |
| Genomic selection is an emerging technology of genetic evaluation in livestock and poultry. Studies
have reported that genomic selection has more advantages than traditional methods，which make it a hot topic in
the field of animal genetic evaluation. However，for species with lower economic importance such as poultry and
swine，it is difficult to genotype all individuals. Single-step procedure integrates not only phenotypes and genetic
markers of genotyped individuals into genomic evaluation，but also field records of non-genotyped individuals
through the pedigree of the population，which is an ideal alternative for genomic evaluation. The application of single
step procedure in pig（ or poultry） genomic selection has attracted much attention，but there are some key issues
to be discussed in practical application. In this paper，the principle of single step procedure，the current status of
implementation and related issues of single step method in livestock were reviewed. |
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