| 梁耀文 1
，舒会友 2，黄新全 3， 陈 玲 4，刘 燊 1
，张辉华 1.重组人乳铁蛋白对断奶仔猪生产性能及血清生化指标的影响[J].广东农业科学,2019,46(9):128-134 |
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重组人乳铁蛋白对断奶仔猪生产性能及血清生化指标的影响 |
| Effects of Recombinant Human Lactoferrin on Growth Performance and Serum Biochemical Index of Weaned Piglets |
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| DOI：10.16768/j.issn.1004-874X.2019.09.018 |
| 中文关键词: 重组乳铁蛋白 断奶仔猪 生产性能 腹泻率 生化指标 抗氧化指标 |
| 英文关键词: recombinant human lactoferrin weaned piglet growth performance diarrhea rate biochemical index antioxidant index |
| 基金项目:国家重点研发计划项目（2018YFD0501202-3）；广东省自然科学基金（2016A030313378）；广东省科技计划项目（2015A020209195）；广东省教育厅高校科研项目（2017GCZX006） |
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| 中文摘要: |
| 【目的】研究重组人乳铁蛋白对断奶仔猪生长性能及血液生化指标的影响。【方法】选取 28 日
龄，体重均匀的断奶仔猪 180 头，试验设 6 个处理，每个处理 3 次重复，每个重复 10 头仔猪（公母各半）。A
处理饲喂基础日粮，作为对照；B 处理添加抗生素，在基础日粮中添加 1 g/kg 10% 的杆菌肽锌 +200 mg/kg 10%
的抗敌素；C、D、E、F 处理在基础日粮基础上分别添加 160、320、480、640 mg/kg 重组人乳铁蛋白。试验为
期 28 d。【结果】（1）试验末重与日均增重 B、C、D、E、F 处理均显著高于 A 处理，日均采食量 B、E 处理
显著高于 A 处理，料重比 B、D、E、F 处理显著低于 A 处理，腹泻指数 B、D、E、F 处理显著低于 A、C 处理。
（2）E 处理血清白蛋白、总蛋白含量显著高于 A 处理，B、E 处理血清尿素氮含量显著低于 A 处理。（3）血
清总抗氧化能力，C、D、E、F 处理显著高于 A 处理。D、F 处理血清谷胱甘肽过氧化物酶活性显著高于 A 处
理，E 处理血清总超氧化物歧化酶活性显著高于 A、B 处理，MDA 浓度 A 处理显著高于 C、D、E、F 处理。【结
论】断奶仔猪日粮中添加重组人乳铁蛋白能提高断奶仔猪生长性能、改善血清生化指标及提高抗氧化能力。
综合试验结果，重组人乳铁蛋白添加量为 480 mg/kg 的效果最好。 |
| 英文摘要: |
| 【Objective】The experiment was conducted to investigate the effects of recombinant human lactoferrin (rHL)
on the growth performance and serum biochemical index of weaned piglets.【Method】One hundred and eighty 28-dayold weaned piglets (with uniform weight), were assigned randomly to 6 treatment groups and there were 3 replicates in each
group with 10 piglets per replicate (5 males and 5 females). The control group A were fed with a basal diet, and group B piglets were fed a basal diet supplemented with antibiotic (1 g/kg 10% bacitracin zinc + 200 mg/kg 10% colistin). Groups C, D,
E and F were fed with basal diets supplemented with 160, 320, 480 and 640 mg/kg rHL, respectively. The experiment lasted
for 28 days.【Result】The results showed as follows: (1) the final weight and average daily gain(ADG) of groups B, C, D, E and
F were higher than those of group A (P ＜ 0.05). The daily intake of groups B and E was significantly higher than that of group
A(P ＜ 0.05). The ratio of weight gain to intake of groups B, D, E and F was significantly lower than that of groups A(P ＜ 0.05).
The diarrhea index of groups B, D, E and F was lower than that of groups A and C(P ＜ 0.05). (2) The concentrations of serum
albumin and TP of group E were higher than that those of group A(P ＜ 0.05). The urea nitrogen of groups B and E was higher
than that of group A(P ＜ 0.05). (3)The T-AOC level of groups C, D, E and F was higher than that of group A(P ＜ 0.05). The
GSH-Px activity of groups D and F was higher than that of group A(P ＜ 0.05). The T-SOD level of group E was higher than that
of groups A and B(P＜ 0.05). The MDA content of group A was lower than that of groups C, D, E and F(P＜ 0.05).【Conclusion】
The above data showed the supplemented rHL could improve the growth performance, serum biochemical index and antioxidant
ability of weaned piglets. The optimum level of rHL was 480 mg/kg based on the test results. |
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