| Andrographis paniculata （Burm. F.） Nees in Acanthaceae, is a traditional Chinese medicinal material.
It is used as medicine from the ground part, which can be antibacterial and antiviral. It is mainly produced in southern China
and is one of the varieties of southern medicine with a high level of large-scale planting. The main medicinal compounds in
A. paniculata are diterpene lactones and flavonoids, which are also the raw materials of many Chinese patent medicines and
can be used as the main components of veterinary drugs. The clinical effects of A. paniculata include protecting the liver and
promoting choleretics, clearing away heat and detoxification, anti-bacterial, and anti-inflammatory, and it is called “antibiotic
of Chinese medicine”. In the past, researches on A. paniculata mostly focused on the pharmacological activity of diterpene
lactones. With the successful annotation of the genome database, related researches on the internal molecular mechanism
such as the generation of its medicinal ingredients will be carried out smoothly. The quality of A. paniculata is unstable,
and the contents of effective active ingredients are affected by many factors such as variety, place of production, cultivation
technology, harvest time and processing technology. As a class of plant-derived antibiotics, the application prospects brought
by standardized planting of A. paniculata will be broad. This article summarizes the research on the pharmacological activity,
active ingredient metabolism, germplasm resource evaluation, innovation and utilization of A. paniculata, soas to provide references for the development and utilization of A. paniculata. |
