Antimicrobial peptides (AMPs) are an important component of the innate immune system of organisms.Owing to their potent, broad-spectrum antibacterial activities and uneasy developing of drug resistance, these peptides have great clinical significance. However, preparation of AMPs at a large scale is a severe challenge to the development of commercial products. Undoubtedly, construction of high-level biological expression systems for the production of AMPs is the key in its clinical application process. This paper summarizes the research progress on heterogenous expression of AMPs in prokaryotic expression systems and eukaryotic expression systems, in order to provide a certain theoretical basis
for research and application of AMPs. |