文章摘要
Research progress on heterogenous expression systems of antimicrobial peptides
  
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Author NameAffiliation
李广京,杨静美,叶滔,胡安龙 深圳职业技术学院应用化学与生物技术学院仲恺农业工程学院农学院广东海纳川药业股份有限公司贵州大学农学院 
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Abstract:
      Antimicrobial peptides (AMPs) are an important component of the innate immune system of organisms.Owing to their potent, broad-spectrum antibacterial activities and uneasy developing of drug resistance, these peptides have great clinical significance. However, preparation of AMPs at a large scale is a severe challenge to the development of commercial products. Undoubtedly, construction of high-level biological expression systems for the production of AMPs is the key in its clinical application process. This paper summarizes the research progress on heterogenous expression of AMPs in prokaryotic expression systems and eukaryotic expression systems, in order to provide a certain theoretical basis for research and application of AMPs.
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