文章摘要
Bioinformatics analysis on the SNP in promoter regionof POLRMT gene in Guizhou local goat
  
DOI:
Author NameAffiliation
孙岩岩,罗卫星,谢海强,宋桃伟,刘彬,蔡惠芬 贵州大学动物科学学院/贵州大学高原山地动物遗传育种与繁殖教育部重点试验室贵州贵阳550025 
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Abstract:
      In order to provide the basic information and scientific proof for better heredity selection of Guizhou Local goats, three goat breeds (Guizhou Write Goat, Guizhou Black Goat and Qianbei Ma Goat) were selected as the experimental subjects for exploring the influence between SNPs which located in the promoter region of POLRMT gene and meat quality. SNPs were screened by constructing the DNA pool, and variety bioinformatics softwares were used to predict the core region of the promoter, CpG island and transfer factors. The results showed that two SNPs (T-81A, T-289C) were found in POLRMT gene. Because of the two SNPs, the range of POLRMT gene core promoter changed, transcription factors disappeared, meanwhile, one CpG island increased.
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