| The reproductive performance of sow, controlled by some QTLs, is an important breeding trait reflecting production level and profitability of one piggery. It has essential economic and scientific value to find the major genes or marks of litter size trait. This research used Genepop software to calculate Fst value of each SNP based on Porcine SNP60 BeadChip of taihu pig breeds and wild boars, and to identify the relative loci for litter size. We selected some SNPs that the Fst values ranked before 0.025%, and then the annotated genes containing these SNPs or the bilateral genes were searched, and submitted to DAVID database to perform GO and KEGG analysis. Results showed that the most significant selective sweep signals located in SSC8 and SSC13. Two SNPs of SCC13 were found in IQCJ-SCHIP1 gene. One SNP of SSC8 was found in NR3C2 gene, having no overlap area refer to previous studies, which may be a new site regarding to litter size trait. Through KEGG analysis, there were two genes in Lysine synthesis pathway. The result indicated that using selective sweep method, we chose taihu pigs and wild boars to identify the SNPs loci influenced the litter size of sow, and found a new SNP site. IQCJ-SCHIP1 gene, NR3C2 gene and two genes in Lysine synthesis pathway could be the candidate genes about litter size. |
