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Predictive analysis of integrative and conjugative elements(ICEs)in completely sequenced Vibrio genomes |
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Abstract: |
Integrative and conjugative elements(ICEs)are selftransmissible mobile genetic elements that
mediate horizontal gene transfer in bacteria. ICEs and related elements can constitute a large proportion of bacterial
chromosomes,and bestow a wide range of phenotypes upon their host with carried gene cassettes. To study the role
of SXT/R391 ICEs in the growth of Vibrio, SXT/R391 ICEs were identified in the 26 completely sequenced Vibrio
genome using PrfC and their characteristic modules. The results showed that only SXT/R391 ICEs were found from 3
V. cholerae,and we comparatively analyzed the resistance genes and hotspots among 3 SXT/R391 ICEs. The region in
resistance genes and hotspots had similar structure in 3 SXT/R391 ICEs,it could indicate the precedence relation in 3
SXT/R391 ICEs based on the genes which lost or gained |
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