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| Tissue distribution of fluoride and its effects on immunerelatedenzymes activities of hepatopancreasin Cipangopaludina cahayensis |
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| Abstract: |
| Tissue distribution of fluoride and its effects on the activities of immune-related enzymes（ACP，
AKP and CAT）were examined in hepatopancreas of Cipangopaludina cahayensis exposed to different concentrations
of fluoride for 60 days. The results showed that the fluoride accumulation in different tissues after exposed to fluoride
significantly increased compared with the control group and the trend which increased and then decreased with the level
and duration of exposure was found. Stead state was achieved under the experimental conditions. The activities of ACP
and AKP first decreased and then increased during the fluoride exposure. After 30 days of exposure，the activities of
ACP and AKP in hepatopancreas exposed to the highest concentration of fluoride highly significantly elevated compared
with the control group. After exposure for 60 days，the activities of ACP and AKP in all fluoride-exposed C. cahayensis
were remarkably lower than those in the control mudsnail. The CAT activity increased first and then decreased and highly
significantly decreased in mudsnail exposed to 80 mg/L
and 160 mg/L of fluoride relative to the control during the
whole exposure. |
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