| Porcine Deltacoronavirus (PDCoV) is a member of the δ-coronavirus, a newly discovered coronavirus
in 2012 which can infect porcine. Such coronavirus is clinically characterized by diarrhea symptoms in sows and piglets
and basically characterized by vomiting, watery diarrhea, dehydration and loss of appetite. The mortality rate of the
infected piglets is 30%-40%. The disease outbroke in the United States in 2014. The disease emerged in our country in
the same year and has spread to many countries and regions in the following years, which brought huge economic losses
to pig industry. At present, a series of test methods have been established for PDCoV infection, test results showed that
PDCoV not only infected pigs alone but also mixed with other porcine intestinal coronavirus to infect pigs. However, up
to now, there are few researches on the pathogenic mechanism of PDCoV and the understanding of the disease is not
comprehensive enough. There is still no effective vaccine for preventing and controlling the emergence of the disease.
In this paper, the current research status of PDCoV genome characteristics, protein function, epidemiology, genetic and
evolutionary analysis, detection methods and prevention and control measures were summarized so as to provide reference
for the study of pathogenic mechanism and clinical research of PDCoV. |
