| 【Objective】This experiment was performed to improve the bioavailability of sodium selenite and
the environmental responsive sodium selenite/sodium alginate microcapsules (SSSAMC) were prepared by endogenous
emulsion method. 【Method】SSSAMC were prepared by using natural macromolecule sodium alginate (SA) as wall
material, sodium selenite (Na2SeO3) as core material and Nano-CaCO3 as cross-linking agent. The thermal stability
and morphology of SSSAMC were analyzed by TG and SEM&EDS. The environmental responsiveness of SSSAMC was
investigated by measuring the swelling ratio of SSSAMC at different pH, temperature and ion concentration, and the
relationship between the swelling degree of SSSAMC and time were analyzed. 【Result】The SSSAMC prepared by this
method got a remarkable thermal stability. At the same time, SSSAMC had the responsiveness of pH, temperature and ion
concentration. Its response swelling process conformed to Schott swelling model, and the correlation coefficient R2 was
over 0.99. 【Conclusion】The results indicated that SSSAMC had both excellent thermal stability and environmental
responsiveness and was expected to be a dietary selenium nutritional agent released by the intestinal tract. |
