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| Study on the Synergism of Two Adjuvants on Bromadiolone Baits |
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| DOI：10.16768/j.issn.1004-874X.2020.08.014 |
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| Abstract: |
| 【Objective】In order to increase the utilization rates and prevention and control effects of anticoagulant rodenticides and reduce their ecological risks, the synergistic effects of two adjuvants on bromadiolone baits were investigated.【Method】The content distribution of bromadiolone in the poison grains prepared by different varieties and concentrations of adjuvants were determined by using high-performance liquid chromatography. The palatability and the toxic effects of the bromodiolone poison grains prepared with different adjuvants for mice were evaluated by selective and non-selective feeding tests.【Result】The content of bromadiolone in the brown rice of 0.01% poison grains treated with 4% N, N-dimethylformamide and 4% dimethyl sulfoxide was significantly higher than that in the 0.01% poison grains, with the increase of 271.17% and 163.51%, respectively. While the content of bromadiolone in the brown rice of 0.0025% poison grains treated with 4% N, N-dimethylformamide and 4% dimethyl sulfoxide was significantly higher than that in the 0.0025% poison grains, with the increase of 433.33% and 400.95%, respectively. The results of bioassay showed that the 0.0025% bromodiolone poison grains with two kinds of adjuvants exhibited good palatability and potent efficacy on mice. Their feeding coefficient were 2.69 and 0.80, with the poison rates of 100% and 90%, which were significantly higher than the poison rate of the 0.0025% bromodiolone poison grains, but there was no significant difference with the 0.01% bromodiolone poison grains.【Conclusion】4% N, N-dimethylformamide and 4% dimethyl sulfoxide showed significant synergistic effects to the bromodiolone poison baits, and decreased the use concentration of rodenticide obviously. |
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