| 温秀萍，邹福贤，卢泽雨，洪 旖，于虹敏，刘小芬，范世明，林 羽.基于质量控制分析不同产地绞股蓝的水分、灰分和浸出物含量[J].广东农业科学,2021,48(5):132-140 |
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基于质量控制分析不同产地绞股蓝的水分、灰分和浸出物含量 |
| Analysis of Moisture, Ash and Extract Contents of Gynostemma pentaphyllum from Different Origins Based on Quality Control |
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| DOI：10.16768/j.issn.1004-874X.2021.05.017 |
| 中文关键词: 药用绞股蓝 茶饮绞股蓝 质量标准 水分 酸不溶性灰分 水溶性浸出物 |
| 英文关键词: medicinal Gynostemma pentaphyllum tea Gynostemma pentaphyllum quality standard moisture acidinsoluble ash water-soluble extract |
| 基金项目:2019 年医疗服务与保障能力提升补助资金（中医药事业传承与发展部分）“全国中药资源普查项目”（财社〔2019〕39 号）；福建省科技厅引导性项目（2018Y0049）；福建省卫生计生科研人才培养项目（2017-1-70，2016-2-28）；福建省教育厅省属高校科研专项（JK2017024） |
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| 中文摘要: |
| 【目的】研究不同产地绞股蓝的水分、灰分和浸出物含量，并设置其质量控制项目和限量，为提升绞股蓝的质量标准提供参考依据。【方法】采用《中国药典》（2020 年版）四部通则中相关检测方法对绞股蓝中的水分、总灰分、酸不溶性灰分、水溶性浸出物的含量进行测定。【结果】不同产地、不同部位的绞股蓝水分、浸出物、总灰分和酸不溶性灰分之间有一定差异。所有 75 批次绞股蓝，全草的含水量最高，与龙须、叶、茎和叶 3 种部位的含水量均具有显著性差异。其中药用绞股蓝水分含量为 8.31%~12.78%，总灰分含量为9.41%~20.19%，酸不溶性灰分含量除样品部位为茎之外的 19 批样品外均在 0.57%~6.99% 范围，水溶性浸出物含量为 20.86%~39.79%。55 批次茶饮绞股蓝中，水分含量仅 14 批次达标，总灰分含量 19 批次合格，产地为陕西、湖北和福建的绞股蓝浸出物含量较其他省份高。【结论】结合试验结果并综合分析药用、茶饮绞股蓝的质量控制，建议制定统一标准。将水分、总灰分、酸不溶性灰分和水溶性浸出物（热提法）4 项检查设为各省绞股蓝药材质量控制项目，拟定药用绞股蓝的水分、总灰分含量分别不得超过 12.0%、16.0%，酸不溶性灰分不高于 3.0%，水溶性浸出物（热浸法）含量不低于 25.0%；茶饮绞股蓝可依据使用部位不同制定相应的质量控制标准。 |
| 英文摘要: |
| 【Objective】The moisture, ash and extract contents of Gynostemma pentaphyllum (GP) from different origins were studied, and the items and limits of quality control were set up with a view to provide references for the improvement of quality standard of GP. 【Method】The contents of moisture, total ash, acid-insoluble ash and water-soluble extracts of GP were determined according to Chinese Pharmacopoeia (2020 Edition).【Result】There were certain differences among the moisture, water-soluble extract, total ash and acid-insoluble ash of GP from different origins and different parts. Among all 75 batches of GP, the moisture content of the whole plant was the highest, which had significant difference compared with that of the three parts of tendrils, leaves and stem mixed with leaves. Among them, the moisture content of medicinal GP ranged from 8.31% to 12.78%; the total ash content ranged from 9.41% to 20.19%; the acid-insoluble ash content in 19 batches of samples (except for stems) ranged from 0.57% to 6.99%; and the water-soluble extract content was between 20.86% and 39.79%. Among 55 batches of tea GP, only 14 batches of moisture content and 19 batches of total ash content were qualified, the extract content of GP from Shaanxi, Hubei and Fujian wan higer than that from other provinces.【Conclusion】Combined with the comprehensive analysis on the quality control of medicinal and tea GP and experimental results, it is recommended that a unified standard should be developed. Four items of moisture, total ash, acid-insoluble ash and water-soluble extracts should be set as quality control inspection items of medicinal GP in each province, including: the moisture content of medicinal GP should not exceed 12.0%, the total ash content should not exceed 16.0%, the acid-insoluble ash content should not exceed 3.0%, and the water-soluble extract content should not be less than 25.0%; while quality control standards of tea GP can be developed based on the use of different parts. |
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